British Air Force Typhoon jets have conducted a mission with France's air force in a combined operation against an underground arms cache in Syria employed by the IS group, according to the British defence ministry.
The site, identified by surveillance, was believed to be storing arms and explosives, the statement said, and was positioned in mountains just above the historic site of Palmyra in the heart of Syria.
"Our fighter planes used precision-guided Paveway IV munitions to target a number of access tunnels providing entry to the depot... initial indications suggest the strike was effective," the ministry announced.
There was no indication of any harm to civilians in the strike late on Saturday and all the aircraft made a safe return, the ministry further stated.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
Daesh - alternatively referred to as Daesh - imposed militant control over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This action underscores our UK leadership, and resolve to stand shoulder to shoulder with our partners, to eliminate any resurgence of Daesh and their dangerous and violent ideologies in the area," UK Defence Secretary the Defence Secretary stated.
RAF aircraft have performed surveillance missions over Syrian airspace to "forestall any attempted resurgence" of IS subsequent to its routing at the Baghuz confrontation in the year 2019, the ministry said.
"I want to thank every member of our armed forces participating in this operation for their professionalism and their valour," he said. "Including them were a great many British personnel stationed over Christmas and New Year. This action, to take out terrorist threats who pose a risk to our way of life, demonstrates how our armed forces are always on standby, continuously, ensuring Britain's security within its borders and influential overseas."
In December, the United States armed forces conducted what it described as a "massive strike" on IS targets in the country, subsequent to an ambush killed two US troops and a local interpreter in the Palmyra area.
The United Nations says Islamic State still has roughly 5-7 thousand combatants in Syria and Iraq.